Input: Gene-Centric Summary Data
Completed on Sun May 26 11:49:06 2024 (Asia/Shanghai), with the runtime of 3 seconds.
An interactive table for user-input summary data (n=298 genes, being processed for subnetwork analysis using
STRINGmm_fin, followed by subnetwork-based effect-by-removal analysis). This table has three columns: 1st columnGenesfor gene symbols, 2nd columnPvaluefor use-input significance information, and 3rd columnDescriptionfor gene description. This table can be downloaded into an excelxlsxfile.
Output: Gene Subnetwork
A network visualisation of the subnetwork, with
30genes/nodes color-coded based on input gene significance information. An editable pdf file is also available for download.
Figure 1: Visualisation of the identified subnetwork, with genes/nodes color-coded by input gene significance information; that is, -log10(pvalue).
An interactive table for the
30subnetwork genes, with the columnPvaluefor input gene significance information. Also available for download is an excelxlsxfile detailing subnetwork results.
Output: Effect-By-Removal Analysis
An upset plot, visually capturing the effect of node removal. An editable pdf file is also available for download.
Figure 2: An upset plot illustrating the fraction of disconnected nodes on the y-axis against node removal (indicated by solid circles beneath) on the x-axis.
An interactive table for the
30subnetwork genes, with the columnFraction of nodes disconnecteddescribing the fraction of nodes disconnected upon the node removal (see the columnRemoved). Also available for download is an excelxlsxfile detailing effect-by-removal results.